Publications by authors named "Annabelle S Chidiac"

Article Synopsis
  • A study on paracetamol dosing errors in Australia showed that unintentional overdoses can lead to serious liver damage, particularly due to small miscalculations in dosage; 14,380 such cases were recorded from 2017 to 2023, with a 2.5% annual increase.
  • In 2021, detailed analysis of 1,899 exposures revealed that 26.8% of individuals required hospitalization; common factors included higher doses, prolonged use, and many using multiple paracetamol products.
  • The findings highlight the need for better education on proper dosing and more noticeable labeling of ingredients to reduce the risk of overdose, as many cases involved patients using paracetamol
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Introduction: Paracetamol is one of the most used medicines worldwide and is the most common important poisoning in high-income countries. In overdose, paracetamol causes dose-dependent hepatotoxicity. Acetylcysteine is an effective antidote, however despite its use hepatotoxicity and many deaths still occur.

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