Publications by authors named "Annabel McAtee"
Article Synopsis
- The study aimed to compare the research experiences and career outcomes of international medical graduates (IMGs) with those of US medical graduates (USMGs) in neurosurgery from 2018 to 2020.
- IMGs had significantly more publications both before and during residency compared to USMGs, indicating higher academic productivity.
- Despite IMGs showing greater early academic appointment rates, there were no significant differences in residency rankings or completion rates of postresidency fellowships between the two groups.
Article Synopsis
- Bioresorbable shape memory polymers (SMPs) like poly(glycerol dodecanedioate) (PGD) offer potential solutions for minimally invasive surgeries by facilitating tissue repair, but they require biocompatibility through the incorporation of bioactive ligands.
- In this study, specific cell-adhesive peptides (RGD and YIGSR) were conjugated to PGD, enhancing cell attachment and proliferation, particularly when both peptides were used together compared to single peptide applications.
- Results indicate that the shape memory cycle conditions affect the functionality and specificity of the peptides, with the arrangement of these peptides after recovery influencing their effectiveness in promoting cell binding, which is crucial for designing functionalized
Awake craniotomy (AC) allows intraoperative brain mapping (ioBM) for maximum lesion resection while monitoring and preserving neurological function. Conventionally, language, visuospatial assessment, and motor functions are mapped, while the assessment of executive functions (EF) is uncommon. Impaired EF may lead to occupational, personal, and social limitations, thus, a compromised quality of life.
View Article and Find Full Text PDFSterilization effects on poly(glycerol dodecanedioate): A biodegradable shape memory elastomer for biomedical applications.
J Biomed Mater Res B Appl Biomater
April 2023
Biodegradable shape memory polymers provide unique regenerative medicine approaches in minimally invasive surgeries. Once heated, thermally responsive shape memory polymer devices can be compressed, programmed to fit within a small profile, delivered in the cold programmed state, and expanded when heated to body temperature. We have previously developed a biodegradable shape memory elastomer (SME), poly(glycerol dodecanedioate) (PGD), with transition temperatures near 37°C exhibiting nonlinear elastic properties like numerous soft tissues.
View Article and Find Full Text PDFThe tumor microenvironment (TME) has been implicated to play an important role in the progression of ovarian cancer. One of the most important components of the TME is tumor associated macrophages (TAMs). Phenotypically, macrophages are broadly categorized as M1 pro-inflammatory or M2 anti-inflammatory, based on the cytokines and chemokines that they secrete.
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