Nonadherence in mood disorders: A formidable challenge in clinical practice.

Nonadherence in mood disorders poses a significant obstacle to remission and recovery. A comprehensive approach that includes evidence-based strategies have been shown to improve adherence customized to the individual needs of the patient resulting in improved quality of life and reduced disease burden. This is further strengthened by identifying risk factors, establishing therapeutic alliances, and educating patients, families and other healthcare providers.