Publications by authors named "Anna-Maria Ioppolo"

Article Synopsis
  • - Percutaneous left atrial appendage closure (LAAC) is being explored as a non-drug option for preventing strokes in patients with atrial fibrillation, but there’s still limited comparative data on its effectiveness versus traditional anticoagulants like vitamin K antagonists (VKAs) and direct oral anticoagulants (DOACs).
  • - A meta-analysis of seven trials involving over 73,000 patients found that LAAC has similar rates of stroke or systemic embolism compared to VKAs and DOACs, and while bleeding risks were similar, LAAC was linked to lower bleeding risk after excluding procedural complications.
  • - Ultimately, both LAAC and DOACs showed lower all-cause mortality compared to VK
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Introduction: Carotid artery angioplasty and stenting (CAS) is an established procedure to treat carotid artery stenosis for either primary or secondary prevention of stroke. Randomized clinical trials have shown an increased risk of periprocedural cerebrovascular events with CAS compared with carotid endarterectomy (CEA). Several strategies have been proposed to mitigate this risk, including alternative vascular access site, proximal/distal embolic protection devices, and dual-layer stents, among others.

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Background: Contrast-induced nephropathy (CIN) can occur after cardiovascular procedures using contrast media, which is associated with increased morbidity and mortality. RenalGuard is a closed-loop system designed to match intravenous hydration with diuretic-induced diuresis that has shown mixed results in the prevention of CIN in previous randomized controlled trials.

Objectives: The STRENGTH (Study Evaluating the Use of RenalGuard to Protect Patients at High Risk of AKI) study assessed whether RenalGuard (PLC Medical Systems) is superior to standard intravenous hydration for CIN prevention in patients with chronic kidney disease undergoing complex cardiovascular procedures.

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Objectives: The aim of this study was to identify independent angiographic predictors of collateral channel (CC) tracking success, microcatheter tracking failure, and complications in chronic total occlusion (CTO) retrograde approach. We also developed a "crossability score," comparing its predictive performance with pre-existing scores.

Background: The retrograde approach was introduced for recanalization of challenging CTOs.

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We describe a case of an 88-year-old woman with a severe bluntly ematic pericardial effusion. Radiological and laboratory examinations excluded all the most common causes of hemopericardium, and the diagnosis of spontaneous hemopericardium associated with the treatment with rivaroxaban was made. This is the first case report describing a hemopericardium in a patient treated with rivaroxaban who did not take other herbal products or drugs that may significantly increase rivaroxaban blood levels.

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