Identification of serum microRNAs with differential expression between dogs with splenic masses and healthy dogs with histologically normal spleens.

Objective: To identify differential microRNA (miRNA) expression in dogs with splenic hemangiosarcoma, splenic hematoma, and histologically normal spleens.

Animals: Dogs with splenic hemangiosarcoma (n = 10), splenic hematoma (n = 5), and histologically normal spleens (n = 5).

Procedures: Splenic tissue and serum samples were collected from dogs with splenic masses (ie, hemangiosarcoma or hematoma samples) and healthy control dogs (ie, control samples), and total RNA was extracted.

A Simulated Tumor for Teaching Principles of Surgical Oncology for Biopsy and Excision of Skin and Subcutaneous Masses to Veterinary Students.

Tumors of the skin and subcutaneous tissues are commonly encountered in primary care practice. The most common of these tumors are mast cell tumors and soft tissue sarcomas, for which the primary treatment is most often surgical excision. Understanding surgical margins, particularly the deep fascial plane, can be difficult for veterinary students.