Quantifying sensory thresholds along the migraine cycle: An exploratory longitudinal study.

Background: To date, a number of studies on migraine have cross-sectionally evaluated sensory sensitivity with aversion thresholds/scores along the migraine cycle, reporting a decreased tolerance to sensory stimuli in different sensory modalities. Our hypothesis was that patients with migraine would exhibit heightened sensitivity to sound, light, touch and smell on days where they reported greater headache intensity.

Methods: This is an exploratory, longitudinal study, carried out over the course of 27 days.