[Osteoporosis risk factors among patients with schizophrenia].

The etiopathogenesis, risk factors and indications for prevention and treatment of osteoporosis in patients with schizophrenia are presented. Accelerated decrease in bone mineral density (BMD) is mostly attributed to antypsychotics (drug-induced hyperprolactinemia and decrease in levels of estrogen and testosterone), insufficient calcium intake, low physical activity and limited exposure to sunshine, alcohol and tobacco intake, polidypsia. Clinical symptoms of osteoporosis (eg.

[Mechanisms of the body weight gain induced by novel antipsychotic drugs and concomitant lipid abnormalities].

The authors presents the state of knowledge on the prevalence and proposed mechanisms leading to weight gain during treatment with atypical antipsychotics. A short review on the therapeutic approaches is also supplied.

[Decrease in mineral bone density in schizophrenic patients treated with 2nd generation antipsychotics].

Unlabelled: Decrease in bone mineral density may lead to osteopenia or osteoporosis. In patients with schizophrenia it may be attributed to medication-related hyperprolactinemia and hypogonadism, low physical activity, smoking, dietary deficiencies, low exposure to sunshine and polydipsia. Many of these factors can be eliminated.

[Calcium balance and regulation in schizophrenic patients treated with second generation antipsychotics].

Unlabelled: Calcium balance and regulation play an important role in providing its normal plasma concentration. Hormonal regulation is mostly done by parathormone and vitamin D. Impaired balance may result in bone demineralization, decreased bone mineral density and cause osteopenia and osteoporosis.

[Prolactin secretion disturbances in schizophrenic patients treated with 2nd generation antipsychotics--risperidone and olanzapine].

Unlabelled: Hyperprolactinemia is an elevation ofprolactin level above the norm in two separate samples. Its prevalence is 0.4%.

[Brain metabolism alterations in patients with anorexia nervosa observed in 1H-MRS].

The causes of metabolic brain changes in patients with anorexia nervosa are still not fully explained. The purpose of this study was to use the 1H-MRS method in investigating metabolic changes in the brain of patients with anorexia nervosa. We studied 10 patients for visible alternations in brain metabolism and compared the results to healthy controls.

[The effects of antipsychotic treatment on the hypothalamo-pituitary-gonadal (HPG) axis in patients with schizophrenia].

The functioning of Hypothalamic-Pituitary-Gonadal axis is commonly affected during a course of antipsychotic therapy. This paper presents epidemiology, possible cause and management of hormonal disturbances during antipsychotic treatment in patients with schizophrenia.