Recombinant multimeric dog allergen prevents airway hyperresponsiveness in a model of asthma marked by vigorous T 2 and T 17 cell responses.

Background: Allergy to dogs affects around 10% of the population in developed countries. Immune therapy of allergic patients with dog allergen extracts has shown limited therapeutic benefit.

Methods: We established a mouse model of dog allergy by repeatedly administering dog dander and epithelium extracts via the intranasal route.

Allergens in dog extracts: Implication for diagnosis and treatment.

Background: Five to ten percent of the population in affluent countries are allergic to dog. Diagnosis and treatment is based on allergen extracts from natural sources where composition and concentration are poorly defined.

Objective: We aimed to quantify six dog allergens (Can f 1-6) in commercial skin prick test (SPT) solutions and to determine individual allergen profiles in dogs.