Publications by authors named "Anna Webber"

Article Synopsis
  • Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis, and the study investigates the role of soluble CD13 (sCD13) and its signaling through the bradykinin receptor B1 (B1R) in SSc pathogenesis.
  • Researchers found elevated levels of CD13, B1R, and MMP14 in skin from SSc patients, which contributed to fibrosis through signaling pathways activated by TGF-β and sCD13.
  • The study concludes that targeting the sCD13-B1R axis could represent a novel and effective therapeutic strategy for treating skin fibrosis in SSc.
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American Indians have substantially higher commercial tobacco-related cancer rates when compared to the general population. To effectively combat commercial tobacco-related cancer, it is important that tribal nations obtain current and accurate community-specific data on commercial tobacco use and exposure-related attitudes and behaviors. With the goal to collect, synthesize, and disseminate data on tobacco use, including the role traditional tobacco plays among American Indian people, the American Indian Cancer Foundation (AICAF) and various stakeholders developed and implemented the Tribal Tobacco Use Project II (TTUP II) during 2018-2021.

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We study an SIS epidemiological model of a population partitioned into groups referred to as communities, households, or patches. The system is studied using stochastic spatial simulations, as well as a system of ordinary differential equations describing moments of the distribution of infectious individuals. The ODE model explicitly includes the population size, as well as the variability in infection levels among communities and the variability among stochastic realizations of the process.

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