Pulse transit time as a surrogate measure of changes in systolic arterial pressure in children during sleep.

Pulse transit time has been proposed as a surrogate measure of systolic arterial pressure, as it is dependent upon arterial stiffness. Past research has shown that pulse transit time has a significant inverse relationship to systolic arterial pressure in adults; however, studies in children are limited. This study aimed to explore the relationship between systolic arterial pressure and pulse transit time in children during sleep.

Long-term changes in neurocognition and behavior following treatment of sleep disordered breathing in school-aged children.

Study Objectives: Sleep disordered breathing (SDB) in children is associated with detrimental neurocognitive and behavioral consequences. The long term impact of treatment on these outcomes is unknown. This study examined the long-term effect of treatment of SDB on neurocognition, academic ability, and behavior in a cohort of school-aged children.

Long-term changes in heart rate variability in elementary school-aged children with sleep-disordered breathing.

Objective: Sleep-disordered breathing (SDB) in adults and children has been associated with reduced heart rate variability (HRV) indicative of autonomic dysfunction, which in turn is associated with an increased risk for cardiovascular morbidity. However, the long-term effects of pediatric SDB that has either resolved or remains unresolved on HRV are unknown.

Methods: Forty Children with previously diagnosed SDB and 20 non snoring controls underwent repeat overnight polysomnography (PSG) four years after the original diagnosis.

Long-term changes in blood pressure control in elementary school-aged children with sleep-disordered breathing.

Objective: In adults sleep-disordered breathing (SDB) has been associated with impaired baroreflex control of blood pressure (BP), which has been linked to increased cardiovascular morbidity. In children, the long-term effects of SDB on baroreflex sensitivity (BRS) and BP variability (BPV) are unknown.

Methods: Children previously diagnosed with SDB (n=40) and 20 nonsnoring controls aged 11-16 y underwent overnight polysomnography with continuous BP measurement, four years after the original diagnosis.

Improvement of sleep-disordered breathing in children is associated with a reduction in overnight blood pressure.

Objective: Childhood sleep-disordered breathing (SDB) is associated with elevated blood pressure (BP); however, little is known about the long-term outcomes in this population. We aimed to assess long-term changes in overnight BP in children with SDB.

Methods: Forty children with previously diagnosed SDB and 20 nonsnoring control participants underwent repeat overnight polysomnography (PSG) with continuous BP measurement 4years after the original diagnosis.

Impaired blood pressure control in children with obstructive sleep apnea.

Background: Obstructive sleep apnea (OSA) in adults has been associated with hypertension, low baroreflex sensitivity (BRS), a delayed heart rate response to changing blood pressure (heart period delay [HPD]), and increased blood pressure variability (BPV). Poor BRS may contribute to hypertension by impairing the control of blood pressure (BP), with increased BPV and HPD. Although children with OSA have elevated BP, there are scant data on BRS, BPV, or HPD in this group.

A four year follow-up of sleep and respiratory measures in elementary school-aged children with sleep disordered breathing.

Objective: Little is known of the long-term prognosis of children treated for sleep disordered breathing (SDB) and even less of children with milder forms of SDB who remain untreated. We aimed to investigate the long-term sleep and respiratory outcomes of children with a range of SDB severities.

Methods: 41 children with SDB and 20 non snoring controls (mean age, 12.

Does treatment of SDB in children improve cardiovascular outcome?

Sleep disordered breathing (SDB) is a common disorder in both adults and children and is caused by the obstruction of the upper airway during sleep. Unlike adults, most cases of paediatric SDB are due to the presence of enlarged tonsils and adenoids, thus the main treatment option is adenotonsillectomy (T&A). It is well known that obstructive sleep apnoea in adults increases the risk for hypertension, coronary artery disease and stroke, and there is now mounting evidence that SDB also has a significant impact on the cardiovascular system in children with reports of elevated blood pressure, endothelial dysfunction and altered autonomic cardiovascular control.