[Paget's disease of bone: new therapeutic strategies].

Paget's disease of bone is a chronic disorder of unknown etiology that can result in enlarged and misshapen bones. The excessive breakdown and formation of bone tissue cause affected bones to weaken, resulting in pain, misshapen bones, fractures, and arthritis in the joints. In most cases the diagnosis is achieved casually, as only 5% of patients develop burning pain at the level of affected bones.

[The treatment of the glucocorticoids-induced osteoporosis: recent knowledge].

Osteoporosis is a skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fractures that affects both cortical bone and trabecular bone. Osteoporosis may be either primary or secondary. Among the secondary forms, the glucocorticoid-induced osteoporosis is most common form that occurs, regardless of age, sex, and even with low doses of glucocorticoid.

[New and old strategies against osteoporosis].

Osteoporosis is a skeletal disorder characterized by compromised bone strength predisposing to an increased risk of fracture that affects both cortical bone and trabecular bone. Osteoporosis may be either primary or secondary. Primary osteoporosis can be distinguished into two types: diffuse or local.