Publications by authors named "Anna V Samodova"
Article Synopsis
- The study investigates how the immune system and blood transport components of people in the Arctic region of Russia adapt to environmental stressors, revealing the body's resilience and functionality.
- The research analyzed blood samples from 191 Arctic residents, measuring indicators like hemoglobin levels, immune cell activity, and cytokine concentrations, using various statistical methods.
- Findings showed high rates of erythrocytosis, thrombocytosis, and leukocytosis among locals, while highlighting reduced active phagocytes and specific lymphocyte populations, alongside increased levels of pro-inflammatory cytokines and circulating immune complexes.
Article Synopsis
- The study aimed to investigate the immune status of the Kola Saami and Russians living in the extreme climates of the Far North, focusing on how climate and genetic factors affect immunological reactivity.
- Researchers conducted a detailed blood analysis on 67 Saami and 81 Russians, examining various immune cells, cytokines, and antibodies through advanced immunological techniques.
- Results indicated that the Saami exhibited lower leukocyte counts and deficiencies in certain immune components, while the Russians showed higher levels of various immune markers, suggesting distinct immune profiles between the two populations.
Article Synopsis
- The study investigates how general hypothermia affects cellular reactions in capillary and venous blood among relatively healthy northerners across different light conditions, focusing on 108 participants aged 21 to 50.
- The researchers performed a wide range of blood tests to measure various immune cell counts and other physiological parameters before and after exposing subjects to extremely cold conditions for five minutes.
- Findings reveal significant differences in blood cell counts between venous and capillary blood, indicating that hypothermia, particularly during polar night, compromises immune function by reducing neutrophils and T-lymphocytes.
Purpose: The purpose of this study is to identify the features of hematological reactions in the inhabitants of the Arctic territory of the Kola Peninsula on a polar night and a polar day.
Methods: The study included determining the hemogram, neutrograms, monocytograms, lymphocytograms, and phagocytic activity neutrophil granulocytes, enzyme immunoassay, flow cytometry.
Results: It was established that during the polar night, there is an increase in the activity of migration of leukocytes from the marginal pool to the circulating pool, an increase in the intensity of phagocytosis by neutrophils, an increase in the concentrations of noradrenaline, cortisol, as well as an increase in hyperergic reactions involving immunoglobulin E and inhibitory processes due to an increase in interleukin-10.