Experimental morphologic study of reparative processes in erosive lesions of the oral mucosa.

The goal of this preclinical study was to substantiate the effectiveness of using autologous platelet-rich plasma (PRP) to heal erosive lesions in the oral cavity. This study employed analyses of qualitative and semiquantitative morphologic parameters, including histologic assessment of biopsy specimens. The most favorable results were observed in a group of 16 dogs receiving 2-mL injections of autologous PRP 3 times: day 1 of the experiment and after 7 and 14 days of observation; in this group, no traces of inflammatory symptoms were found at the end of the observation period (14 days).