Publications by authors named "Anna V Lynch"
J Am Soc Nephrol
December 2024
Article Synopsis
- * A study reviewed 21 MLIV patients and conducted experiments on MLIV mouse models to understand kidney function, revealing that adult patients often have chronic kidney disease along with altered kidney functions and structure in the mice due to issues with endolysosomal function and autophagy.
- * Results showed decreased kidney function, presence of fibrosis and inflammation in MLIV models, and impaired uptake of essential proteins, which highlights cellular and systemic dysfunction in the
