Publications by authors named "Anna Shawcross"
Article Synopsis
- LCI (Lung Clearance Index) is a useful tool for assessing lung function in cystic fibrosis (CF), but its clinical use has been limited due to technical issues and interpretation difficulties.
- A 3-year study involving 112 patients with CF revealed that a majority maintained stable LCI measurements, even among those with normal lung function scores, suggesting that LCI can effectively identify patients at risk for lung function decline.
- Analysis showed that baseline LCI is a significant predictor of future changes in lung function, indicating the potential for LCI to be integrated into clinical practice for monitoring patients with CF.
Background: Lung clearance index (LCI), measured using multiple breath inert gas washout (MBW) is a potentially useful test in infants with respiratory disease, particularly cystic fibrosis (CF). Clinical use is limited however by the need for specialist staff and equipment. We have previously described a novel method for infant MBW suitable for use outside of specialist laboratories.
View Article and Find Full Text PDFHighlights from the 30th North American Cystic Fibrosis Conference, Orlando 2016.
Paediatr Respir Rev
March 2018
This is a selection of papers presented at the 30th North American Cystic Fibrosis Conference held in Orlando in October 2016. The papers discussed are thought to be of particular interest to CF caregivers in the UK. We highlight the major themes covered in the conference including novel therapies, recently published and proposed guidelines and insights from registry studies.
View Article and Find Full Text PDFBackground: Multiple breath washout (MBW) in infants presents a number of technical challenges. Conventional MBW is based on simultaneous measurement of flow and gas concentrations. These two signals are aligned and combined to derive expired gas volumes from which lung volumes and measures of ventilation inhomogeneity are calculated.
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