Publications by authors named "Anna R Kimata"

Article Synopsis
  • Responsive neurostimulation (RNS) is a treatment for people with hard-to-control epilepsy, especially when surgery isn't an option.*
  • The case discussed is about a patient with many brain problems and seizures that come from different areas of the brain, showing that the seizures are more complicated than coming from just one spot.*
  • After using RNS to target the areas involved, the patient went from having 5 seizures a day to none, which suggests that this treatment can work well for people with difficult epilepsy.*
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The responsive neurostimulator system has become increasingly popular in the surgical management of refractory epilepsy, with targeting of various thalamic nuclei showing promising results in select patients. A 42-year-old female presented for evaluation of refractory epilepsy consisting of generalized tonic-clonic and focal seizures with preserved awareness. Phase I and II monitoring suggested multifocal bilateral epilepsy with bilateral frontal onset, and the patient underwent robot-guided bilateral centromedian thalamic placement of the RNS System.

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Understanding the role of the pulvinar nucleus may be critical for guiding circuit-targeted neurosurgical intervention in some patients. In this report, a 33-year-old female presented with focal onset occipital epilepsy with secondary generalization and with a previously radiated arteriovenous malformation within the right primary visual cortex. Phase II monitoring demonstrated the pulvinar nucleus was not involved in subclinical seizures restricted to the primary visual cortex, but it did become involved in clinical events with more extensive seizure spread into higher visual cortical regions.

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Article Synopsis
  • Responsive neurostimulation (RNS) is used to diagnose and treat epilepsy that doesn't respond to medication, helping doctors understand patients' seizure patterns better.
  • A patient with epilepsy underwent RNS treatment and later had surgery on one side of the brain after RNS data indicated that seizures were more frequent from that side.
  • The study found that after the surgery, there was a decrease in seizure activity on the opposite side, suggesting that using RNS data can improve surgical outcomes and protect brain function.
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Background And Objectives: Preoperative embolization of arteriovenous malformations (AVMs) remains controversial. This study sought to analyze the cost-effectiveness of preoperative embolization of AVMs.

Methods: Patients who underwent AVM resection at a single institute (January 1, 2015-December 31, 2020) were analyzed.

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Lag-1 sparing is a common exception to the attentional blink, where a target presented directly after T1 can be identified and reported accurately. Prior work has proposed potential mechanisms for lag 1 sparing, including the boost and bounce model and the attentional gating model. Here, we apply a rapid serial visual presentation task to investigate the temporal limitations of lag 1 sparing by testing three distinct hypotheses.

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Introduction: Epilepsy is a common, often debilitating disease of hyperexcitable neural networks. While medically intractable cases may benefit from surgery, there may be no single, well-localized focus for resection or ablation. In such cases, approaching the disease from a network-based perspective may be beneficial.

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Background: Studies have shown an association between surgical treatment volume and improved quality metrics. This study evaluated nationwide results in carotid artery stenting (CAS) procedural readmission rates, costs, and length of stay based on hospital treatment volume.

Methods: We used the Nationwide Readmissions Database for carotid stenosis from 2010 to 2015.

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Article Synopsis
  • - The study aimed to understand how frailty affects outcomes for patients with traumatic intracranial hemorrhage (tICH) by analyzing data from the National Trauma Data Bank between 2007 and 2017.
  • - It was found that 18% of the patients were frail, and frailty significantly increased the odds of mortality and complications, while decreasing the likelihood of favorable recovery after treatment.
  • - The findings indicate that frailty is linked to longer hospital stays and more intensive care needs, highlighting its independent role in predicting worse outcomes for tICH patients, regardless of their age or severity of injury.
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Background: Cerebral arteriovenous malformations (AVMs) with low Spetzler-Martin grades (I and II) are associated with good neurological outcomes after microsurgical resection; however, the use of preoperative embolization for these lesions is controversial.

Objective: To compare the neurological outcomes of preoperative embolization with no embolization in patients with low-grade AVMs.

Methods: Patients with a Spetzler-Martin grade I or II AVM who underwent microsurgical resection during January 1, 1997, through December 31, 2019, were analyzed.

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Objective: The brainstem cavernous malformation (BSCM) grading system predicts neurological outcomes associated with microsurgical resection and assists neurosurgeons in selecting patients for treatment. The predictive accuracy of the BSCM grading system should be validated in a large cohort from high-volume centers to generalize its use.

Methods: An external validation cohort comprised patients with a BSCM resected by the senior author (M.

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Background: The COVID-19 pandemic has significantly affected patient care across specialties. Ramifications for neurosurgery include substantial disruptions to surgical training and changes in nonurgent patient presentations to the emergency department. This study quantifies the effects of the COVID-19 pandemic on the number of emergency department patients who were referred to the neurosurgery department for further consultation and treatment and identifies and describes trends in the characteristics of these visits.

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Objective: Previous research has demonstrated the association between increased hospital volume and improved outcomes for a wide range of neurosurgical conditions, including adult neurotrauma. The authors aimed to determine if such a relationship was also present in the care of pediatric neurotrauma patients.

Methods: The authors identified 106,146 pediatric admissions for traumatic intracranial hemorrhage (tICH) in the National Inpatient Sample (NIS) for the period 2002-2014 and 34,017 admissions in the National Trauma Data Bank (NTDB) for 2012-2015.

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