Proliferative vitreoretinopathy.

Proliferative vitreoretinopathy is a sophisticated disease that complicates vitreoretinal pathologies like retinal detachments. Since its first description in the 1960s, we have learned a lot about this pathological entity; however, despite a large number of promising laboratory and clinical pharmacological research projects, we are still unable to stop proliferation and are certainly not able to prevent this terrible complication. As a result, vitreoretinal surgeons still have to fight membrane formation in complicated and long vitreoretinal procedures.