Perfluorosulfonic Acid Membranes with Short and Long Side Chains and Their Use in Sensors for the Determination of Markers of Viral Diseases in Saliva.

The development of accessible express methods to determine markers of viral diseases in saliva is currently an actual problem. Novel cross-sensitive sensors based on Donnan potential with bio-comparable perfluorosulfonic acid membranes for the determination of salivary viral markers (-acetyl--methionine, -carnitine, and -lysine) were proposed. Membranes were formed by casting from dispersions of Nafion or Aquivion in -methyl-2-pyrollidone or in a mixture of isopropyl alcohol and water.

Potentiometric Sensor Arrays Based on Hybrid PFSA/CNTs Membranes for the Analysis of UV-Degraded Drugs.

The degradation of drugs is a substantial problem since it affects the safety and effectiveness of pharmaceutical products, as well as their influence on the environment. A novel system of three potentiometric cross-sensitive sensors (using the Donnan potential (DP) as an analytical signal) and a reference electrode was developed for the analysis of UV-degraded sulfacetamide drugs. The membranes for DP-sensors were prepared by a casting procedure from a dispersion of perfluorosulfonic acid (PFSA) polymer, containing carbon nanotubes (CNTs), whose surface was preliminarily modified with carboxyl, sulfonic acid, or (3-aminopropyl)trimethoxysilanol groups.

Perfluorosulfonic Acid Membranes Modified with Polyaniline and Hydrothermally Treated for Potentiometric Sensor Arrays for the Analysis of Combination Drugs.

A novel potentiometric multisensory system for the analysis of sulfamethoxazole and trimethoprim combination drugs was developed. The potentiometric sensors (Donnan potential (DP) was used as an analytical signal) with an inner reference solution were based on perfluorosulfonic acid (PFSA) membranes modified with polyaniline (PANI) by in situ oxidative polymerization. The order of the membrane treatment with precursor solutions and their concentrations was varied.

Correlation between Nafion Morphology in Various Dispersion Liquids and Properties of the Cast Membranes.

Nafion is a perfluorosulfonic acid polymer that is most commonly used in proton-exchange membrane fuel cells. The processes of pretreatment and formation of such membranes strongly affect their properties. In this work, dispersions of Nafion in various ionic forms and dispersing liquids (ethylene glycol, -dimethylformamide, -methyl-2-pyrrolidone and isopropyl alcohol-water mixtures in different ratios) were obtained and studied.

Multisensory Systems Based on Perfluorosulfonic Acid Membranes Modified with Functionalized CNTs for Determination of Sulfamethoxazole and Trimethoprim in Pharmaceuticals.

Sulfamethoxazole and trimethoprim are synthetic bacteriostatic drugs. A potentiometric multisensory system for the analysis of sulfamethoxazole and trimethoprim combination drugs was developed. Perfluorosulfonic acid membranes containing functionalized CNTs were used as the sensor materials.

Multisensory Systems Based on Perfluorosulfonic Acid Membranes Modified with Polyaniline and PEDOT for Multicomponent Analysis of Sulfacetamide Pharmaceuticals.

The degradation of sulfacetamide with the formation of sulfanilamide leads to a deterioration in the quality of pharmaceuticals. In this work, potentiometric sensors for the simultaneous determination of sulfanilamide, sulfacetamide and inorganic ions, and for assessing the degradation of pharmaceuticals were developed. A multisensory approach was used for this purpose.

Perfluorosulfonic Acid Membranes Thermally Treated and Modified by Dopants with Proton-Acceptor Properties for Asparaginate and Potassium Ions Determination in Pharmaceuticals.

The influence of incorporation of the dopants with proton-acceptor properties into perfluorosulfonic acid cation exchange membranes (MF-4SC and Nafion), and their treatment conditions on the characteristics of Donnan potential (DP)-sensors (analytical signal is the Donnan potential) in the aqueous solutions containing asparaginate and potassium ions in a wide pH range was investigated. A silica, surface modified by 3-aminopropyl and 3-(2-imidazolin-1-yl)-propyl groups, was used as the dopant. The membranes were subjected to mechanical deformation and thermal treatment at various relative humidities.