The "Prisoner's Dilemma" in the Tumor Biology Context: The Warburg Effect, Proliferation Dynamics and Equilibria.

There are numerous theories concerning carcinogenesis. Starting from the Warburg effect, which was one of the first theories concerning the mitochondrial dysfunction in tumor cells. Further on, the "two-hit" theory, where tumors were considered to be the outcome of genetic aberrations or mutations and more specifically of a certain number of "hits" each one resulting in a mutation.

Bioinformatics and Regression Analyses Manifest Tumor-Specific miRNA Expression Dynamics in Pediatric Embryonal Malignancies.

Pediatric Central Nervous System (CNS) neoplasms are the second most prevalent tumors of childhood. Further on, prognosis of this type of neoplasms still remain poor and the comprehension of the etiology and pathogenesis of the disease still remains scarce. Several reports have identified microRNAs as significant molecules in the development of central nervous system tumors and propose that they might compose key molecules underlying oncogenesis.

Education in health and nursing informatics.

This chapter focused on some of the key issues of Health and Nursing Informatics Education. First an historical overview of Health and Nursing Informatics Education is presented. We also describe briefly the activities in the domain of Nursing Informatics Education across Europe.