Attitude and practice of regenerative endodontic procedures among endodontists and paediatric dentists: A multinational survey from 13 countries.

Background: Regenerative endodontics (RET) refers to biologically based procedures that aim to restore damaged tooth structures and reinstate the pulp-dentine complex to its normal physiological state.

Aim: The purpose of this study was to examine the attitudes and practices of endodontists and paediatric dentists regarding RET.

Design: A survey was conducted among endodontists and paediatric dentists from 13 countries.

Design of non-cytotoxic 6,7-dihydroxycoumarin-5-carboxylates with antibiofilm activity against and .

The 6,7-dihydroxycoumarin-5-carboxylates DHCou and 4-Me-DHCou have been synthesized five-step route including a propargyl-Claisen rearrangement as key step. The compounds show antibiofilm activity against and but lack the cytotoxic activity of parent 6,7-dihydroxycoumarines such as esculetin and 4-methylesculetin.

Assessment of the Prevalence of Middle Mesial Canal in Mandibular First Molar: A Multinational Cross-sectional Study with Meta-analysis.

Background: An additional canal found in the mandibular first molar (M1M) is the middle mesial canal (MMC), which is often missed during root canal treatment. In this study, the prevalence of MMC in M1M on cone-beam computed tomography (CBCT) images was evaluated in 15 countries, along with the effect of some demographic factors on its prevalence.

Methods: Deidentified CBCT images were scanned retrospectively, and the ones including bilateral M1Ms were included in the study.

Characteristics of salivary inflammation in obesity.

Introduction: The discovery of the secretory function of adipose tissue has led to a new direction in research on obesity‑ related health problems. Adipokines are present not only in blood but also in saliva. Numerous studies have indicated that obesity affects salivary concentrations of adipokines.