[Intrapartum prophylaxis against group B Streptococcus infection--own experience].

Introduction: Group B Streptococcus (GBS) infection is a leading cause of neonatal complications.

Objectives: The aim of the following work was to assess the efficacy of the intrapartum antibiotic prophylaxis (IAP) of the GBS infection, together with the diagnostic and therapeutic management of the newborn, based on the type and frequency of neonatal complications in the children of GBS carriers.

Material And Methods: 2212 patients, who gave birth at the 1st Department of Obstetrics and Gynecology Medical University of Warsaw, between January 2007 and March 2008, were included in the study.

The polymorphism in insulin receptor substrate-1 gene and birth weight in neonates at term.

Background: The mutation of the IRS-1 gene is one of the genetic risk factors which, it is speculated, is associated with insulin resistance or predisposition to type 2 diabetes. The aim of our study was to evaluate the association between the Gly972Arg polymorphism in the IRS-1 gene and birth weight in newborn children with adequate gestational age.

Material And Methods: 100 newborn children with adequate gestational age (38-42 weeks), whose mother had no disorders during pregnancy, were studied.

Decreased human milk concentration of epidermal growth factor after preterm delivery of intrauterine growth-restricted newborns.

Background And Aim: The aim of the study was to compare epidermal growth factor (EGF) concentration in 81 colostrum samples collected from mothers of newborns in the following growth categories: preterm appropriate for gestational age (AGA), preterm small for gestational age (SGA), and full term (FT).

Results: Significantly higher concentrations of EGF were found in the colostrum of mothers who delivered premature AGA infants at less than 32 weeks of gestation compared with mothers who delivered premature SGA babies at the same gestational age.

Conclusions: We concluded that the maternal compensatory mechanism accelerating the development of immature breast-fed infants may be disturbed when gestation is complicated by intrauterine growth retardation.

[Mediastinal tumor as a cause of fetal hydrops].

Unusual case of fetal hydrops was presented. In a stillborn infant an Rh incompatibility was suspected as a cause of hydrops, although prentally an immunologic source of the illness was excluded. Post-mortem a large polycystic mediastinal teratoma with cardiac and pulmonary hypoplasia was stated as a main cause of the hydrops.