Serum concentrations of interleukin-2 soluble receptor (IL-2 sR) in patients with vitiligo: relationship with type and extent of the disease.

Vitiligo is a disorder of melanin pigmentation, affecting 1-2% of general population. The etiopathogenesis of the disease is not clear, but probably includes the interaction among nervous system, cytotoxic factors, and immune mechanisms. The aim of the study was to evaluate serum concentrations of interleukin-2 soluble receptor (IL-2 sR) in patients with vitiligo and assess a possible association between IL-2 sR and clinical type, extent, and duration of the disease.