Publications by authors named "Anna Norberg Hardie"
Article Synopsis
- In the FIGO 2018 classification, women with early-stage cervical cancer are now classified differently based on their tumor's size and spread, which could change how they are treated.
- A study looked at a group of 992 women with specific types of cervical cancer to see how often the cancer spread to lymph nodes (pN+) and found that certain factors like lymphovascular space invasion (LVSI) increased the risk of spread.
- The results suggest that women with LVSI-positive tumors should have lymph node checks, but those with LVSI-negative tumors may not need this if their tumor size and other factors are considered.
Background: According to international guidelines, standard treatment (ST) with curative intent in cervical cancer (CC) comprises radical hysterectomy and pelvic lymphadenectomy in early stages (International Federation of Gynecology and Obstetrics (FIGO) 2009 IB1, IIA1), adjuvant chemoradiation is recommended based on risk factors upon final pathology. Definitive chemoradiation is recommended in locally advanced stages (FIGO 2009 IB2, IIA2, IIB). Total mesometrial resection (TMMR) with therapeutic lymph node dissection (tLND) without adjuvant radiation has emerged as a promising treatment.
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