C-methacetin breath test reproducibility study reveals persistent CYP1A2 stimulation on repeat examinations.

Aim: To find the most reproducible quantitative parameter of a standard (13)C-methacetin breath test ((13)C-MBT).

Methods: Twenty healthy volunteers (10 female, 10 male) underwent the (13)C-MBT after intake of 75 mg (13)C-methacetin p.o.