Publications by authors named "Anna Nikopoulou"

This case report outlines the diagnostic and therapeutic challenges encountered in a man in his 70s suffering from knee septic arthritis caused by It is the second published case in the literature with osteoarticular infection from and the first one in the last 40 years. Following knee arthroscopy, the patient experienced persistent pain, swelling and discomfort, prompting further investigation. Postoperative knee cultures were negative for infection, but symptoms were not ameliorated.

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is a difficult-to-treat, multidrug-resistant human pathogen. Relebactam has been shown to inhibit β-lactamase (BLA) and increase the activity of imipenem and amoxicillin. We present two cases of lung infection due to , one caused by subsp and the other by subsp.

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The aim was to highlight the incidence and epidemiology of infections (CDI) in a tertiary Greek hospital during the COVID-19 pandemic. A single-center prospective observational cohort study was conducted (October 2021 until April 2022). 125 isolates were cultured from hospitalized patients stool samples and screened by PCR for toxin A (), toxin B (), binary toxin ( and ) genes and the regulating gene of .

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Candida auris is an emerging fungal pathogen associated with multi-drug resistance rates and widespread outbreaks in hospitals and healthcare units worldwide. Sequencing studies have revealed that different clonal lineages of the fungus seem to be prevalent among distinct geographical sites. The first case of C.

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Article Synopsis
  • Skin and soft tissue infections from non-tuberculous mycobacteria are increasing in frequency, posing diagnostic challenges for healthcare providers.
  • A case study of a 66-year-old male showed painful nodules on his arm, worsened by anti-TNF-a treatment, and confirmed positive for mycobacteria after extensive testing.
  • The paper reviews the complexities of diagnosing and managing these infections, highlighting current trends in epidemiology, clinical characteristics, and treatment approaches.
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infection (CDI) represents an important global threat. In the COVID-19 era, the multifactorial nature of CDI has emerged. The aim was to assess the impact of COVID-19 pandemic on the incidence of CDI in a Greek hospital.

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Background: Gut microbiota is well-known for its ability to maintain intestinal homeostasis. However, the disruption of this homeostasis, known as dysbiosis, leads to multiple consequences, including local and systemic inflammation. Surgery-induced inflammation is a major concern for patients, as it leads to many infectious and non-infectious complications.

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: The importance of gut microbiota in human health is being increasingly studied. Imbalances in gut microbiota have been associated with infection, inflammation, and obesity. Antibiotic use is the most common and significant cause of major alterations in the composition and function of the gut microbiota and can result in colonization with multidrug-resistant bacteria.

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Medicine shortages result in great risk for the continuity of patient care especially for antimicrobial treatment, potentially enhancing resistance rates and having a higher economic impact. This study aims to identify, describe, assess, and assign risk priority levels to potential failures following substitution of antimicrobial treatment due to shortages among European hospitals. Furthermore, the study investigated the impact of corrective actions on risk reduction so as to provide guidance and improve future patient care.

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