A novel water-soluble polymer nanocomposite containing ultra-small FeO nanoparticles with strong antibacterial and antibiofilm activity.

A novel water-soluble polymer nanocomposite containing ultra-small iron oxide nanoparticles, intercalated into a biocompatible matrix of 1-vinyl-1,2,4-triazole and -vinylpyrrolidone copolymer has been synthesized for the first time. The use of an original polymer matrix ensured effective stabilization of the crystalline phase of iron oxides at an early stage of its formation in an ultra-small (2-8 nm, average diameter is 4.8 nm) nanosized state due to its effective interaction with the functional groups of copolymer macromolecules.

Spontaneous Transformation of Biomedical Polymeric Silver Salt into a Nanocomposite: Physical-Chemical and Antimicrobial Properties Dramatically Depend on the Initial Preparation State.

An antimicrobial polyacrylic silver salt (freshly prepared, stored for one year and model-aged) was studied by physical-chemical techniques for nanoparticle detection. In all cases, this salt represents a composite of radical-enriched macromolecules and silver(0) nanoparticles. As time passed, the initial small spherical nanoparticles were converted into larger non-spherical silver nanoparticles.