Metabolic Disorders Induced by Fructosedrinking Water Affect Angiotensin II-mediated Intestinal Contractility in Male Wistar Rats.

Introduction: The high-fructose diet in rats has been reported to cause metabolic disorders such as impaired fasting glucose levels, in-sulin resistance, dyslipidemia, and dysregulation of the renin-angiotensin system. This could lead to further complications, for instance, to the smooth muscle dysfunction.

Aim: The present study aimed at developing fructose-induced metabolic perturbations in rats and the investigation of their impact on angiotensin II-induced smooth muscle intestinal motility.

Hepatoprotective properties of Curcuma longa L. extract in bleomycin-induced chronic hepatotoxicity.

Curcuma longa L. (CLL) extract has previously been reported to alleviate liver damage. The current study examined the antioxidant activity of CLL by which the extract protects the liver against bleomycin (BLM)-induced hepatotoxicity in mice.

Fructose-induced metabolic disturbances in rats and its impact on stomach endocrine cell number and smooth muscle contractility.

Gastric ghrelin-positive endocrine cells (GHR + EC) were most dense in the oxyntic mucosa. We evaluated ECs and contractile activity in rat stomach with metabolic disorders. Male Wistar rats were divided into two groups: Control ( = 9) received tap water and Fructose ( = 9) drank 15% fructose solution for 12 weeks.