Drops of madness? Recreational misuse of tropicamide collyrium; early warning alerts from Russia and Italy.

Background: Tropicamide is an antimuscarinic drug usually prescribed as an ophthalmic solution to induce short-term mydriasis and cycloplegia. Over the last 2 years, tropicamide has been reported in both Russia and Italy to be self-administered intravenously (IV) for recreational purposes.

Methods: The literature on tropicamide was searched in PsycInfo and Pubmed databases.