Bone marrow undergoes significant changes with age, transitioning from red to yellow marrow and displaying distinct histological features that can be detected by MRI, particularly through high signal intensity on T2 images due to increased free water.
Chronic nonbacterial osteomyelitis (CNO) is an idiopathic inflammatory condition in children, marked by nonspecific pain and variable MR imaging signs, commonly diagnosed by ruling out other conditions.
The review aims to outline the characteristics of CNO and distinguish it from similar conditions, including various malignancies and benign lesions that may appear on imaging.