Development of Thyme-Infused Polydimethylsiloxane Composites for Enhanced Antibacterial Wound Dressings.

Polydimethylsiloxane (PDMS) is widely used in biomedical applications due to its biocompatibility and flexibility but faces challenges due to its hydrophobicity and limited mechanical strength. This study explores the incorporation of thyme ( L.) into PDMS to enhance its properties for wound dressing applications.

The Effect of Exposure to Candida Albicans Suspension on the Properties of Silicone Dental Soft Lining Material.

While functioning in the oral cavity, denture soft linings (SL) are exposed to contact with the microbiota. Dentures can offer perfect conditions for the multiplication of pathogenic yeast-like fungi, resulting in rapid colonisation of the surface of the materials used. In vitro experiments have also shown that yeast may penetrate SL.

Red/Orange Autofluorescence in Selected Candida Strains Exposed to 405 nm Laser Light.

Background: and similar species are significant pathogens in immunocompromised and hospitalized individuals, known for mucosal colonization and bloodstream/organ invasion. Many pathogenic including these species, exhibit autofluorescence (R/OF) under specific light conditions, a feature crucial for their detection.

Aim: We investigated the use of a 405 nm diode laser for the direct observation of red/orange autofluorescence of spp.

A Temporary Acrylic Soft Denture Lining Material Enriched with Silver-Releasing Filler-Cytotoxicity, Mechanical and Antifungal Properties.

Colonization of temporary denture soft linings and underlying tissues by yeast-like fungi is an important clinical problem due to the negative influence on the process of prosthetic treatment. Typical hygienic procedures are often insufficient to prevent fungal infections, so in this study, an antimicrobial filler (silver sodium hydrogen zirconium phosphate) was introduced into acrylic soft liner at concentrations of 1, 2, 4, 6, 8 and 10% (/). The effect of this modification on antifungal properties against , cytotoxicity, Shore A hardness, tensile strength and tensile bond strength, sorption and solubility was investigated, considering the recommended 30-day period of temporary soft lining use.

The effect of quaternary ammonium polyethylenimine nanoparticles on bacterial adherence, cytotoxicity, and physical and mechanical properties of experimental dental composites.

A significant problem related to the functioning of resin-based composites for dental fillings is secondary or recurrent caries, which is the reason for the need for repeated treatment. The cross-linked quaternary ammonium polyethylenimine nanoparticles (QA-PEI-NPs) have been shown to be a promising antibacterial agent against different bacteria, including cariogenic ones. However, little is known about the properties of dental dimethacrylate polymer-based composites enriched with QA-PEI-NPs.

The Impact of COVID-19 on the Oral Bacterial Flora in Patients Wearing Complete Dentures and on the Level of Exhaled Nitric Oxide as a Marker of Inflammation.

Background: Exhaled nitric oxide is helpful in the diagnosis of the inflammation process. The study aimed to analyze the impact of the COVID-19 disease on the oral bacterial flora of patients using complete dentures with a diagnostic device that measures the level of NO in exhaled air.

Materials And Methods: The study included patients using upper and lower acrylic complete dentures.

Evaluation of the Sensitivity of Selected Strains to Ozonated Water-An In Vitro Study.

(1) Oral candidiasis has increased significantly in recent years. Increasingly, we encounter treatment difficulties related to drug resistance. Therefore, it is necessary to search for other therapies such as ozone therapy, which has antimicrobial activity.

Analysis of the Validity of Perioperative Antibiotic Prophylaxis in Maxillofacial Surgery.

Perioperative antibiotic prophylaxis is the standard in surgical departments. The type of operation, the duration of the procedure, the degree of microbiological purity of the operating field and the current clinical condition of the patient determine its administration. The aim of this study was to validate the antibiotic prophylaxis used in a Maxillofacial Surgery Department for a group of trauma and non-trauma patients.

Status of Microbiota in Odontogenic Inflammatory Lesions and Dental Surgery Procedures Performed on an Outpatient Basis.

Inflammations of the facial part of the skull are most commonly caused by a bacterial infection. They are a frequently occurring pathological process, which results from a rich bacterial flora of the oral cavity, as well as diseased teeth and periodontal tissues. These inflammations have a primarily mixed character with the prevalence of anaerobic bacteria.

Effect of Suspension on the Mechanical Properties of Denture Base Acrylic Resin.

Yeast-like fungi such as () are the primary pathogenic microorganism in the oral cavity of denture wearers. The research available so far, conducted according to a protocol based on the exposure of specimens to a suspension and their cutting with water cooling, shows that hard polymethyl methacrylate (PMMA) prosthetic materials are not only surface colonized, but also penetrated by microorganisms in a short time. This justifies the hypothesis that exposure to a suspension of the strain causes the changes in mechanical properties due to surface colonization and/or penetration of the samples.

Advantages of using toothpaste containing propolis and plant oils for gingivitis prevention and oral cavity hygiene in cleft lip/palate patients.

Background: The anti-inflammatory and antibacterial action of preparations used during oral hygiene procedures is particularly important in patients with oral cleft. Few reports have been published assessing the influence of natural products on the state of the oral cavity in patients with oral cleft. The aim of this study was to assess the effect of toothpaste containing Polish propolis and plant oils on oral cavity health in patients with oral cleft treated orthodontically.

Evaluation of Effectiveness of a Toothpaste Containing Tea Tree Oil and Ethanolic Extract of Propolis on the Improvement of Oral Health in Patients Using Removable Partial Dentures.

The aim of this study was to evaluate the effect of toothpaste containing natural tea tree essential oil (TTO) and ethanolic extract of propolis (EEP), on microflora and selected indicators of oral health in patients using removable acrylic partial dentures. Fifty patients with varying conditions of hygiene were divided into two groups. The study group received the toothpaste with TTO and EEP, while the control group received the same toothpaste but without TTO and EEP.

Study of Cytotoxic Properties of an Experimental Preparation with Features of a Dental Infiltrant.

Microinvasive dentistry is based on the treatment of early carious lesions with the use of dental infiltrants. The commercially available Icon dental infiltrant does not contain any bacteriostatic component. An experimental preparation enriched with the missing component was synthesised.

Oral microbiota in children with type 1 diabetes mellitus.

Introduction: The oral cavity is a unique ecosystem in which the microbiome is formed by the colonization of billions of bacteria, viruses, and fungi. Aim of the study was to assess the quality and quantity of bacterial microbiota of the oral cavity in children with type 1 diabetes in comparison to healthy children.

Material And Methods: The study group consisted of 50 randomly selected type 1 diabetic children aged 10-18 years divided into 2 groups (25 people each) according to the level of diabetes control: well-controlled group (WC) - HbA1c ≤ 7.

Effect of Weight Loss Surgery on Biomarkers of Angiogenesis in Obese Patients.

Background: The present study aims to clarify the effects of weight loss on biomarkers associated with angiogenesis in patients who underwent laparoscopic sleeve gastrectomy (SG) or adjustable gastric banding (LAGB) in the 12-month follow-up study.

Materials And Methods: We studied 24 obese patients who underwent laparoscopic weight loss surgery, 13 of whom underwent SG and 11 of whom underwent LAGB. We evaluated the circulating level of angiogenesis biomarkers preoperatively and 12 months after surgery.

Evaluation of Drug Susceptibility of Microorganisms in Odontogenic Inflammations and Dental Surgery Procedures Performed on an Outpatient Basis.

Bacterial infections are the most common cause of purulent soft tissue inflammations in the head and neck area. These bacteria are also responsible for the majority of inflammatory complications after third molar removal. The key to success of antibacterial treatment in both cases is the use of an appropriate antibacterial agent.

The relationship between the rheological behavior of RBCs and angiogenesis in the morbidly obese.

Objective: The aim of this study was to investigate the relationship between red blood cell (RBC) aggregation and deformability and angiogenesis parameters in obese patients.

Methods: We studied 35 obese subjects and 20 non-obese people as a control group. Angiogenesis was detected using Bio-Plex Pro Human Angiogenesis Multiplex Assays.

Properties of Experimental Dental Composites Containing Antibacterial Silver-Releasing Filler. Materials 2018, 11, 1031.

In the published article, "Properties of Experimental Dental Composites Containing Antibacterial Silver-Releasing Filler" [...

Properties of Experimental Dental Composites Containing Antibacterial Silver-Releasing Filler.

Secondary caries is one of the important issues related to using dental composite restorations. Effective prevention of cariogenic bacteria survival may reduce this problem. The aim of this study was to evaluate the antibacterial activity and physical properties of composite materials with silver sodium hydrogen zirconium phosphate (SSHZP).

The effects of venous hemodynamics on angiogenesis in morbid obese.

Background: It is known that obesity is associated with alterations in blood rheology and venous hemodynamics. Another recent study has confirmed that adipose tissue is actively involved in angiogenesis through secretion of biologically active substances.

Objective: The aim of this study was to investigate the impact on the venous haemodynamics of the femoral vein on angiogenesis status in morbidly obese patients.

Effect of Silver-Emitting Filler on Antimicrobial and Mechanical Properties of Soft Denture Lining Material.

Colonization of silicone-based soft lining materials by pathogenic yeast-type fungi is a common problem associated with the use of dentures. In this study, silver sodium hydrogen zirconium phosphate (SSHZP) was introduced into polydimethylsiloxane-based material as an antimicrobial filler at concentrations of 0.25, 0.

The Influence of Toothpaste Containing Australian Melaleuca alternifolia Oil and Ethanolic Extract of Polish Propolis on Oral Hygiene and Microbiome in Patients Requiring Conservative Procedures.

The study was based on the use of a toothpaste with antiphlogistic activity, containing Australian oil (tea tree oil-TTO) and ethanolic extract of Polish propolis (EEP). Fifty-one patients with varying conditions of the gingiva were divided into two groups. The study group received the toothpaste with TTO and EEP, while the control group received the same toothpaste but without TTO and EEP.

Novel Triazole Hybrids of Betulin: Synthesis and Biological Activity Profile.

Betulin derivatives containing a 1,2,3-triazole ring possess a wide spectrum of biological activities, including antiviral, anticancer, and antibacterial activity. A series of novel triazoles were prepared by the 1,3-dipolar cycloaddition reaction between the alkyne derivatives of betulin and organic azides. The chemical structures of the obtained compounds were defined by ¹H and C NMR, IR, and high-resolution mass spectrometry (HR-MS) analysis.

Secretion of the angiogenic factor VEGF after photodynamic therapy with ALA under hypoxia-like conditions in colon cancer cells.

Background: Photodynamic therapy (PDT), eliminates not only the tumor, but also modulates signaling factors release, e.g. vascular endothelial growth factor (VEGF), which plays a crucial role in cancer progression.

The analysis of cytotoxicity of an experimental preparation used for the reduction of dentin hypersensitivity.

Background: The problem of effective treatment of dentin hypersensitivity is still valid and not fully resolved.

Objectives: The aim of the study was to evaluate the potential toxicity against body tissues of an experimental preparation which is supposed to reduce dentin hypersensitivity and to compare it to a commercial formulation Seal & Protect (Dentsply) by means of measuring the activity of mitochondrial dehydrogenases (the MTT assay).

Material And Methods: The study used an original protective formulation which is supposed to eliminate hypersensitivity of dentin.