Publications by authors named "Anna Melissa Noronha Oliveira"
Article Synopsis
- - Cerebrotendinous xanthomatosis (CTX) is a genetic disorder marked by a deficiency in sterol 27-hydroxylase, leading to dangerous buildups of cholestanol and bile alcohols in the brain, tendons, and nerves.
- - A review of literature highlighted that CTX patients typically show elevated cholestanol levels while having normal or low serum cholesterol levels; this dyslipidemia may indicate increased risk for atherosclerosis and cardiovascular issues.
- - The study suggests the potential use of cholesterol metabolites, like bile alcohols, as follow-up markers for monitoring CTX due to their relationship with abnormal lipid profiles and associated clinical symptoms.
