Publications by authors named "Anna Maria Pieri"
Purpose: Prostate specific antigen acceleration can be calculated as the slope of log prostate specific antigen vs time, where log is the natural logarithm. We determined the best interval in which prostate specific antigen acceleration can be calculated with the best result in terms of specificity and sensitivity for prostate cancer diagnosis.
Materials And Methods: Entered in the study were 741 men who underwent transrectal ultrasound guided prostate biopsy with 12 or more cores and at least 3 prior consecutive prostate specific antigen measurements in at least 365 days.
Purpose: We developed a predictive model that incorporates clinical data and prostate specific antigen kinetic from general practice to detect prostate cancer in patients with a previously negative prostate biopsy.
Materials And Methods: From January 2001 to January 2007 data on 419 men who underwent repeat prostate biopsy with 12 or more cores were used to develop the nomogram. From February 2007 to June 2007 data on 63 men with the same criteria were used to validate the nomogram.
Objectives: To compare different tools for evaluate prostate-specific antigen (PSA) kinetics before prostate biopsy, such as PSA velocity, PSA slope, natural logarithm PSA slope (lnPSA slope), and PSA doubling time (PSADT).
Methods: This study was conducted involving 325 male patients evaluated with transrectal ultrasound-guided biopsy of prostate. Patients with at least three consecutive PSA measurements taken in at least 24 months entered in the study.