Publications by authors named "Anna M Chichura"
Article Synopsis
- - This review discusses a phase II clinical trial that compared the effectiveness of adjuvant trastuzumab emtansine (T-DM1) with a combination of paclitaxel and trastuzumab (TH) for treating stage I HER2-positive breast cancer, as studied in the ATEMPT trial.
- - Results showed that patients receiving T-DM1 experienced better disease-free survival, meaning they had a lower chance of cancer returning after treatment.
- - However, the T-DM1 group also faced more treatment-related discontinuations and did not have fewer toxicities, indicating that further long-term follow-up is necessary to assess overall survival benefits between T-DM1 and TH.
Background: Time to treatment has been identified as a quality metric, with longer time to treatment associated with poorer outcomes. Genetic evaluation is an integral part of treatment counseling for patients with breast cancer. With expanding indications for genetic testing and consideration of expansion of genetic testing to all patients with a personal history of breast cancer, this study aims to evaluate the effect of genetic evaluation on the time interval from initial surgical visit to surgery.
View Article and Find Full Text PDFStudy Objective: To compare the feasibility of opportunistic bilateral salpingectomy (OBS) at the time of vaginal hysterectomy (VH) for benign disease in patients with and without relative contraindications (RCs) to the vaginal approach and to evaluate the factors that contribute to the inability to perform OBS.
Design: Retrospective chart review.
Setting: Tertiary medical center.