Publications by authors named "Anna Linko-Parvinen"

Objectives: Preanalytical phase is an elemental part of laboratory diagnostics, but is prone to humane errors. The aim of this study was to evaluate performance in preanalytical phase external quality assessment (EQA) cases. We also suggest preventive actions for risk mitigation.

View Article and Find Full Text PDF

Objectives: Elevations of cardiac troponin T (cTnT) levels are common after strenuous exercise. We assessed whether the composition of cTnT release after marathon race differs from that of acute myocardial infarction (MI).

Methods: Troponin composition was analysed in plasma samples taken from 45 runners after marathon race and from 84 patients with type 1 MI.

View Article and Find Full Text PDF
Article Synopsis
  • Cardiac troponin levels, elevated in Takotsubo syndrome (TTS), show significant overlap with acute myocardial infarction (MI), prompting a study on their fragmentation.
  • The study measured long forms of cardiac troponin T (cTnT) in TTS (24 patients) versus Type 1 MI (84 patients), finding a notably lower troponin ratio in TTS, which indicates different cTnT fragmentation patterns.
  • Results suggest that the troponin ratio is more effective than total cTnT in differentiating between TTS and MI, highlighting its potential as a diagnostic tool for elevated cTnT levels.
View Article and Find Full Text PDF

Objectives: Although laboratory result presentation may lead to information overload and subsequent missed or delayed diagnosis, little has been done in the past to improve this post-analytical issue. We aimed to investigate the efficiency, efficacy and user satisfaction of alternative report formats.

Methods: We redesigned cumulative (sparkline format) and single reports (improved tabular and z-log format) and tested these on 46 physicians, nurses and medical students in comparison to the classical tabular formats, by asking standardized questions on general items on the reports as well as on suspected diagnosis and follow-up treatment or diagnostics.

View Article and Find Full Text PDF

European Union (EU) Directive 2013/55/EC (The Recognition of Professional Qualifications) allows Member States to decide on a common set of minimum knowledge, skills and competences that are needed to pursue a given profession through a Common Training Framework. To be adopted the framework must combine the knowledge, skills and competences of at least one third of the Member States. Professionals who have gained their qualifications under a Common Training Framework will be able to have these recognised automatically within the Union.

View Article and Find Full Text PDF

In laboratory medicine, much effort has been put into analytical quality in the past decades, making this medical profession one of the most standardized with the lowest rates of error. However, even the best analytical quality cannot compensate for errors or low quality in the pre or postanalytical phase of the total testing process. Guidelines for data reporting focus solely on defined data elements, which have to be provided alongside the analytical test results.

View Article and Find Full Text PDF

Background: Booster vaccination against tetanus and diphtheria at 10-year intervals is commonly recommended. Reduced antigen content diphtheria and tetanus toxoids and acellular pertussis (dTpa) vaccines developed for booster vaccination of preschool children, adolescents, and adults are licensed for once-in-a-lifetime use in most countries. Objective.

View Article and Find Full Text PDF