Publications by authors named "Anna Lamoureux"
Article Synopsis
- Research on various inbred mouse strains has advanced our understanding of genetic variants linked to diseases, with a vast array of traits cataloged for public access.* -
- New mouse models and enhanced genomic data sets help improve trait-variant analysis, although issues like sparse genotypes and data incompatibility remain obstacles.* -
- The development of GenomeMUSter, a comprehensive data resource, addresses these issues by offering extensive single-nucleotide variant data, facilitating cross-species comparisons and broadening the applications in genetic research related to health and disease.*
Article Synopsis
- Researchers have developed the GenomeMUSter data resource to improve the analysis of genetic variants in laboratory mouse strains, helping to better understand complex diseases.
- This resource features detailed allelic data for 657 mouse strains at over 106 million segregating sites, which aids in linking various traits to genetic variants.
- The platform also allows for integration with phenotype databases and supports advanced analyses, such as comparing mouse and human data for conditions like Type 2 Diabetes and substance use disorders, enhancing genetics research in health.
Article Synopsis
- - The Mouse Phenome Database is a curated repository that provides detailed information and tools for analyzing attributes of various mouse populations, including 657 mouse strains and community standard ontologies.
- - It has evolved from focusing on inbred strains to encompassing diverse populations like the Diversity Outbred and Collaborative Cross, and recently includes data from the International Mouse Phenotyping Consortium.
- - The database offers an interactive tool suite for users to perform analyses such as correlation and trait pattern matching, supporting research on phenotypic variation related to health and disease across different lifespans.
Article Synopsis
- - The Mouse Phenome Database (MPD) is a comprehensive resource that collects and organizes phenotype and genotype data from mouse studies, supported by the NIH and compliant with FAIR data principles.
- - MPD features data from over 6000 mouse strains and populations, incorporating various characteristics related to genetics, behavior, morphology, and disease, and provides detailed metadata to enhance data usability.
- - The database includes analysis tools for users to visualize and aggregate data from different studies, ensuring access to high-quality, reproducible results that are relevant for translational research.
Visualizing regions of conserved synteny between two genomes is supported by numerous software applications. However, none of the current applications allow researchers to select genome features to display or highlight in blocks of synteny based on the annotated biological properties of the features (e.g.
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