Publications by authors named "Anna La Dine"

Article Synopsis
  • Intracranial solitary fibrous tumors (ISFTs) are rare tumors from the meninges, often misdiagnosed due to their similarities with other brain tumors, and display unpredictable clinical behaviors despite being previously considered benign.
  • A case report details the malignant transformation of an ISFT in a 60-year-old female after radiation therapy, showcasing a progression from a benign diagnosis to a malignant one after recurrence.
  • This study highlights the importance of understanding the complex behavior of ISFTs and suggests that their clinical trajectory can vary significantly, which poses challenges for diagnosis and treatment.
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Objective: In the current era of modern neurosurgery, the treatment strategies have been shifted to "nerve-preservation approaches" for achieving a higher facial and hearing function preservation rate following facial nerve tumors. We have conducted this novel report on determining the outcome of patients with facial nerve schwannomas (FNS) treated with hypofractionated stereotactic radiosurgery (hfSRS).

Patients: Retrospective chart review of a prospectively maintained database search was conducted.

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Introduction: Segmental neurofibromatosis (SNF) is a rare subtype of neurofibromatosis (NF). The disease is characterized by features circumscribed to one or more body cutaneous and/or subcutaneous segments. This is a classic example of somatic mosaicism which occurs by postzygotic mut ation of the NF1 gene late in the course of embryonic development affecting localized neural crest lines in the fetus.

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Objective: Cerebellopontine angle (CPA) meningiomas can affect hearing function and require expeditious treatment to prevent permanent hearing loss. The authors sought to determine the factors associated with functional hearing outcome in CPA meningioma patients treated with surgery and/or radiation therapy in the form of either stereotactic radiosurgery or stereotactic radiation therapy.

Methods: Consecutive patients with CPA meningiomas who had presented at our hospital from 2008 to 2018 were identified through retrospective chart review.

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