Publications by authors named "Anna L Iouchmanov"

Article Synopsis
  • Impaired attention is a key cognitive issue for TBI survivors, impacting their recovery and daily life.
  • A study tested rats with moderate TBI using a task designed to mimic human attention tests, showing that both male and female rats had decreased accuracy and increased errors post-injury.
  • Results indicate that these attention deficits are significant and lasting, especially when cues are presented on one side, which relates to a common clinical condition called hemispatial neglect.
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Article Synopsis
  • Reptiles, particularly ball pythons, exhibit a wide variety of colors and patterns, yet most pigment research has focused on other species like mice and zebrafish.
  • This study identifies a genetic mutation in the tfec gene that causes the piebald coloring in ball pythons, characterized by patches of unpigmented skin.
  • The research also demonstrates that tfec is crucial for the development of chromatophores (pigment cells) by using gene editing techniques in a lizard model, underscoring the importance of ball pythons in coloration studies.
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Traumatic brain injuries (TBIs) affect more than 10 million patients annually worldwide, causing long-term cognitive and psychosocial impairments. Frontal lobe TBIs commonly impair executive function, but laboratory models typically focus primarily on spatial learning and declarative memory. We implemented a multi-modal approach for clinically relevant cognitive-behavioral assessments of frontal lobe function in rats with TBI and assessed treatment benefits of the serotonin-norepinephrine reuptake inhibitor, milnacipran (MLN).

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