Publications by authors named "Anna Krupa-Laska"

Peanut allergy, one of the most frequently occurring allergies, usually starts in childhood and rarely subsides-often persisting throughout adult life. Accidental exposure to peanuts can often result in adverse reactions ranging from mild to life-threatening, such as anaphylactic shock. Historically, food avoidance and the use of rescue drugs have remained a fundamental management mechanism for dealing with food allergy.

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Introduction: Sesame allergy, though with low prevalence, can result in severe, potentially life-threatening reactions and poses challenges in allergen avoidance due to hidden sources. In the majority of patients, sesame allergy persists and there is currently no effective long-term treatment available. Therefore, oral immunotherapy (OIT) is a promising alternative approach to managing sesame allergy.

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Article Synopsis
  • Peanut allergy poses a serious risk of anaphylaxis, which might be mitigated through oral immunotherapy based on patient food challenges and antibody assessments against key peanut proteins.
  • A study with 74 peanut-sensitized children explored the links between specific antibodies, food challenge results, skin tests, and other factors, dividing participants into two groups based on challenge responses.
  • The findings indicated distinct differences in skin test results and antibody levels between the groups; while antibody-based predictions had some statistical relevance, they did not accurately predict severe symptoms or anaphylaxis risk, suggesting more research is needed for clinical application.
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