Publications by authors named "Anna Kouril"
J Mol Cell Cardiol
November 2024
Article Synopsis
- Metabolic syndrome increases the risk of coronary artery disease and affects heart function, which was studied in female mice fed a Western diet compared to those on regular chow.
- Mice on the Western diet showed increased body weight and left ventricular mass but maintained systolic and diastolic function, alongside reduced heart rate variability indicating altered cardiac balance.
- Myocytes from these mice exhibited changes in size and mechanics, with heightened cAMP and PKA activity; interventions affecting this pathway improved their function, suggesting adaptations to maintain heart performance despite diet-induced metabolic issues.
