Temporal and Spatial Expression of TGF-b1 in the Early Phase of Patellar Tendon Healing after Application of Platelet Rich Plasma.

Background: The aim of this study is to find out the spatial and temporal expression of TGF-b1 during the tendon healing, after application of Platelet Rich Plasma (PRP).

Methods: A patellar tendon defect model in rabbits was used for this purpose. 48 skeletally mature New Zealand White rabbits, weighing 3.

Temporal and spatial expression of TGF-beta1 in an Achilles tendon section model after application of platelet-rich plasma.

Background: To investigate the effect of platelet-rich plasma (PRP) on TGF-beta1 expression during tendon healing.

Methods: We used 48 skeletally mature New Zealand White rabbits. 24 rabbits received the PRP, and 24 rabbits served as an untreated control group.

Application of PRP gel alone or in combination with guided bone regeneration does not enhance bone healing process: An experimental study in rabbits.

Introduction: The aim of this study was to assess the hypothesis that application of platelet-rich plasma (PRP) gel in mandibular defects in rabbits, alone or in combination with guided bone regeneration (GBR) techniques, could enhance the bone healing process.

Materials And Methods: Thirty New Zealand white rabbits were used. Three groups of 10 animals each were assigned, and the animals were sacrificed after 12 weeks.

Fractures of the femoral neck treated with hemiarthroplasty. A comparative study.

Introduction: Hemiarthroplasty is the treatment of choice in the management of displaced intracapsular fractures of the proximal femur in old patients with low functional demands.

Aim: To assess the effectiveness of cementless Austin-Moore and the cemented Thompson prostheses used in the treatment of displaced intracapsular fractures of the proximal femur.

Patients And Methods: We studied retrospectively 376 patients with fresh, displaced, nonpathological femur neck fractures.

The influence of platelet-rich plasma on angiogenesis during the early phase of tendon healing.

Background: The poor vascularity of tendons is a major factor in their limited healing capacity. The aim of this study was to assess the effect of Platelet Rich Plasma (PRP) on angiogenesis during tendon healing.

Materials And Methods: Forty-eight skeletally mature New Zealand White rabbits were used.

The effect of platelet-rich plasma gel in the early phase of patellar tendon healing.

Introduction: The aim of this study is to assess if an application of platelet-rich plasma (PRP) gel would improve the mechanical properties of rabbit's patellar tendon after resecting its central portion.

Materials And Methods: Forty skeletally mature New Zealand White rabbits were used. Two groups ten rabbits each (PRP and control group) were used to evaluate mechanical properties and histology after 14 days and two groups ten rabbits each (PRP and control groups) were used to evaluate mechanical properties and histology after 28 days.

Immunohistochemical study of angiogenesis after local administration of platelet-rich plasma in a patellar tendon defect.

A full thickness defect was made in the central portion of the patellar tendon of 48 New Zealand white rabbits. Platelet-rich plasma (PRP) gel was then applied and filled the tendon defect. The same procedure was performed in the control group, without the application of PRP.