Publications by authors named "Anna Koike"
Article Synopsis
- The study investigated how catecholamine metabolites affect smooth muscle relaxation in tracheas and aorta of different animals, revealing that metadrenaline notably relaxed guinea pig trachea.
- In the presence of enzyme inhibitors, normetadrenaline and metadrenaline showed mixed effects on isoprenaline-induced relaxation, highlighting their complex interactions.
- The findings suggest that these metabolites can either enhance or inhibit β-adrenoceptor-mediated relaxation, potentially contributing to conditions like pheochromocytoma associated with high catecholamine levels.
Topical or oral azole antifungals are commonly used in canine atopic dermatitis (AD), as the lipophilic yeast Malassezia pachydermatis exacerbates canine AD. To examine whether canine AD lesions harbor azole-resistant M. pachydermatis isolates in East Asia, we investigated the in vitro susceptibility of M.
View Article and Find Full Text PDFIsolates of the yeast Malassezia pachydermatis obtained from skin samples of healthy dogs and of dogs with atopic dermatitis in Japan, Taiwan and Korea were molecularly characterized using intergenic pacer 1 (IGS1) region analysis. The percentage of IGS1 subtype isolates detected in healthy skin was as follows: 1A (6%), 1B (27%), 1C (11%), 2A (6%), 2B (6%), 3A (11%), 3B (6%), 3C (3%) and 3D (24%). In contrast, the most prevalent isolates detected in skin lesions of atopic dermatitis were subtype 3D in Japan and Taiwan and subtype 3C in Korea.
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