Publications by authors named "Anna Klunk"
Quality improvement and quality assurance form a complementary and independent relationship. Quality assurance measures compliance against industry standards using audits, whereas quality improvement is a continuous process focused on processes and systems that can improve care. The Model for Improvement is a robust quality improvement tool that transplant and cellular therapy teams can use to redesign healthcare processes.
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- Transplant-associated thrombotic microangiopathy (TA-TMA) is a serious complication that occurs in patients undergoing hematopoietic stem cell transplantation (HSCT), with a much higher incidence rate found in a single-center study compared to older studies that did not use systematic screening.
- In a multicenter study involving 614 pediatric patients, TA-TMA was found in 16% of cases diagnosed within a median of 22 days after transplant, affecting their health outcomes significantly.
- Results showed that patients with TA-TMA had higher rates of infections and longer hospital stays, leading to a lower overall survival rate (78%) compared to those without TA-TMA (93%), highlighting the importance of systematic screening for better patient management