Publications by authors named "Anna Kellermayer"

Article Synopsis
  • Acute brain slices are commonly used to study the central nervous system, but the impact of injury on microglial cells—the brain's immune system—remains unclear.
  • This study examines how microglial cells change over time and affect neuron function and network organization in these slices, showing that they respond to injury.
  • The findings indicate that microglia play a crucial role in maintaining neuronal network integrity, and their dysfunction leads to significant impairments in brain activity both in the lab and in living organisms.
View Article and Find Full Text PDF

Microglia, the resident immune cells of the brain, play important roles during development. Although bi-directional communication between microglia and neuronal progenitors or immature neurons has been demonstrated, the main sites of interaction and the underlying mechanisms remain elusive. By using advanced methods, here we provide evidence that microglial processes form specialized contacts with the cell bodies of developing neurons throughout embryonic, early postnatal, and adult neurogenesis.

View Article and Find Full Text PDF