Publications by authors named "Anna Kathryn Burch"
Providing value to patients and providers via a pediatric statewide antibiogram in South Carolina.
Antimicrob Steward Healthc Epidemiol
April 2023
Objective: Antimicrobial stewardship has special challenges in particular populations and facilities, including pediatrics. We sought to augment the information available to antimicrobial stewardship programs (ASPs) by created a cumulative statewide antibiogram for neonatal and pediatric populations.
Methods: In the Antimicrobial Stewardship Collaborative of South Carolina (ASC-SC), we created statewide antibiograms, including a separate antibiogram accounting for the pediatric and neonatal intensive care unit (NICU) populations.
Introduction: Treating recurrent multidrug resistant (MDR) urosepsis in pediatric transplant recipients can be challenging. Particularly when antibiotics fail to prevent future occurrence and the nidus is seemingly undiscoverable. While there is an increasing amount of data on phage therapy, to our knowledge, there are no published cases involving pediatric renal transplant recipients.
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- The study analyzed 112 deaths attributed to SARS-CoV-2 among individuals under 21 in the U.S. between February and July 2020, highlighting demographic and clinical characteristics.* -
- Most decedents were male (63%), with a median age of 17, and a significant number identified as Black (28%) or Hispanic (46%); many had underlying health conditions like obesity and asthma.* -
- Children who died from COVID-19 were more likely to have pre-existing health issues compared to those who met criteria for multisystem inflammatory syndrome (MIS-C), which affected 14% of the decedents.*
Objective: No studies, to our knowledge, have determined the relationship between symptom resolution and timing of antimicrobial discontinuation in necrotizing enterocolitis (NEC). Our study seeks to determine the period to NEC resolution by using severity-guided management, based on surrogate markers used in the diagnosis of NEC.
Methods: This retrospective, observational review included patients in our NICU with NEC from June 1, 2012, to June 1, 2018.
Treatment options for Achromobacter xylosoxidans are limited. Eight cystic fibrosis patients with A. xylosoxidans were treated with 12 cefiderocol courses.
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- Since February 2020, the U.S. has reported about 6.5 million COVID-19 cases and approximately 190,000 deaths, with a focus on individuals under 21 years old.
- Among the 121 deaths in this age group during the early pandemic, 63% were males, and most were aged between 10-20 years, with a significant percentage being Hispanic and Black.
- About 75% of those who died had underlying medical conditions, highlighting the need for ongoing monitoring and effective prevention strategies as schools reopen.
Cystic fibrosis is associated with significant morbidity and early mortality due to recurrent acute and chronic lung infections. The chronic use of multiple antibiotics without pathogen eradication increases the possibility of extensive drug resistance or even pan-drug resistance (PDR). It is imperative that new or alternative treatment options be explored.
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