Publications by authors named "Anna K Matveeva"
Article Synopsis
- Researchers aimed to develop a cellular model to study the effects of tumor necrosis factor (TNF) depending on the presence or absence of TNFR1 and TNFR2 receptors in cell lines.
- They created TNFR1 knockout versions of ZR-75/1 and K-562 cell lines to analyze how this absence affects receptor distribution, cell cycle, cell death, and gene expression in response to TNF.
- Findings showed that removing TNFR1 led to changes in TNFR2 distribution, influencing sensitivity to TNF and altering cell proliferation and death patterns in different ways across the two cell lines.
Deletion of BST2 Cytoplasmic and Transmembrane N-Terminal Domains Results in SARS-CoV, SARS-CoV-2, and Influenza Virus Production Suppression in a Vero Cell Line.
Alexander A Dolskiy Sergei A Bodnev Anastasia A Nazarenko Anastasia M Smirnova Olga G Pyankova Anna K Matveeva
Front Mol Biosci
December 2020
SARS-CoV-2, which emerged in Wuhan (China), has become a great worldwide problem in 2020 and has led to more than 1,000,000 deaths worldwide. Many laboratories are searching for ways to fight this pandemic. We studied the action of the cellular antiviral protein tetherin, which is encoded by the BST2 gene.
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