Publications by authors named "Anna Jon Rasmussen"
Article Synopsis
- - Animal germline development and fertility depend on specialized versions of general transcription factors that help activate specific genes for germ cell differentiation, particularly through testis-specific TBP-associated factors (tTAFs).
- - Research shows that a testis-specific version of the polymerase-associated factor 1 complex (tPAF) is crucial for properly terminating transcription from tTAF-activated genes; mutations in tPAF lead to improper gene expression and fertility issues in males.
- - The study reveals that tPAF not only supports the expression of genes important for male fertility but also plays a key role in chromosome segregation during meiosis, suggesting that transcription termination is essential for maintaining germ cell-specific gene activity.
