Publications by authors named "Anna Jessica D Silva"
Healthcare workers exposed to COVID-19 patients present an inflammatory status and Th2/Th17/Th22 immune profile: findings from before vaccine application in Brazil.
An Acad Bras Cienc
June 2023
Article Synopsis
- Healthcare workers are at a higher risk of SARS-CoV-2 infection due to their exposure to infected patients, necessitating a study of their clinical and immunological status.
- A study involving 50 healthcare professionals in Brazil revealed that most participants were women over 50 years old working as nursing technicians, with around 56% testing positive for previous COVID-19 infection.
- Immunological findings indicated signs of light inflammation and a distinct immune response in positive workers, highlighting the need for further research on the long-term effects of continuous virus exposure in this group.
Memory elicitation, T-cell response and antibody production: an independent study of an inactivated entire virus vaccine (Coronavac).
An Acad Bras Cienc
July 2022
Health professionals working to mitigate the COVID-19 pandemic are one of the main risk groups for the disease, being prioritized for vaccination. Considering this, the aim of this study was to analyze the immune response of these professionals immunized with CoronaVac in the first and second doses. Blood samples were collected after the first and second doses of the vaccine (CoronaVac) and used to investigate hematological and biochemical parameters, analysis of immunoglobulin production, cytokines, and gene expression profile, as well as the identification of subsets of immune cells.
View Article and Find Full Text PDFThe severe consequences of ZIKV infection and its emergence and re-emergence in several countries have boosted vaccines' development. Yeasts such as Pichia pastoris has been widely employed as antigen carriers for immunization against infectious agents. Components of the yeast cell wall have immunostimulatory properties, and recombinant antigens can be anchored to the cell surface to enhance the presentation to the immune system.
View Article and Find Full Text PDF