Clinical Puzzles and Decision-Making in Antisynthetase Syndrome.

We present a challenging clinical case of an antisynthetase syndrome (ASS) with a four-year follow-up. The disease debuted with skin manifestations and interstitial lung disease (ILD), then the severe Raynaud's phenomenon came to the fore with the development of occlusive vasculopathy and critical digital ischemia. After the relief of vascular lesions, the severity of the condition was determined by ILD.

Blood lipids and anthropometric parameters in healthy subjects practicing yoga or resistance training in leisure time. What matters: type or intensity of physical activity?

Aim: The aim of the present study was to assess effects of yoga and resistance trainings on blood lipids and anthropometric parameters in people without cardiovascular diseases.

Materials And Methods: Cross-sectional study, which included 167 subjects, was conducted. Subjects regularly practicing yoga or resistance training not less than 2 times a week for a period more than one year were included in the study.

The Role of Genetic Polymorphism in the Formation of Arterial Hypertension, Type 2 Diabetes and their Comorbidity.

Background: Hereditary component plays a significant role in the formation of insulin resistance (IR) - one of the pathogenetic links of arterial hypertension (AH) and type 2 diabetes mellitus (DM2). However, the genetic predisposition to IR can not be realized and does not manifest itself clinically in the absence of appropriate factors of the environment (excessive nutrition, low physical activity, etc.).

Studies on membrane permeability of zebrafish (Danio rerio) oocytes in the presence of different cryoprotectants.

Investigation into fish oocyte membrane permeability is essential for developing successful protocols for their cryopreservation. The aim of the present work was to study the permeability of the zebrafish (Danio rerio) oocyte membrane to water and cryoprotectants before cryopreservation protocol design. The study was conducted on stage III and stage V zebrafish oocytes.

Studies on chilling sensitivity of zebrafish (Danio rerio) oocytes.

Human activity in the last few decades has had a devastating effect on the diversity of fresh water and marine fish. Further decline of fish population may have serious economic and ecological consequences. One of the most promising techniques to preserve fish population is to cryopreserve their germ cells.