Publications by authors named "Anna Horitani"

Article Synopsis
  • The study analyzed non-cancerous Barrett's esophagus (BE) samples from patients, comparing them to samples from patients with esophageal adenocarcinoma (EAC).
  • The researchers found a specific marker was present in only 22.7% of EAC tissue, but it was more common in EAC and linked to aggressive disease characteristics.
  • Additionally, they discovered that the amount of this marker in non-cancerous BE correlated with conditions like hiatal hernia and telomere shortening, suggesting a potential connection between Barrett's esophagus and esophageal cancer.
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DNA methylation is involved in esophageal adenocarcinoma (EAC) and Barrett's esophagus (BE). Microarchitectures of on-neoplastic BE associated with DNA methylation status were examined using magnifying narrow-band imaging (NBI) endoscopy. Using biopsies from non-neoplastic BE without cancer (n = 66; N group), with EAC (n = 27; ADJ group) and EAC tissue (n = 22; T group), methylation of and  genes were quantified.

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