Machine Learning-Based Prediction of Chronic Shunt-Dependent Hydrocephalus After Spontaneous Subarachnoid Hemorrhage.

Background: Chronic posthemorrhagic hydrocephalus often arises following spontaneous subarachnoid hemorrhage (SAH). Timely identification of patients predisposed to develop chronic shunt-dependent hydrocephalus may significantly enhance clinical outcomes.

Methods: We performed an analysis of 510 SAH patients treated at our institution between 2013 and 2018.

Turning the operating room into a mixed-reality environment: a prospective clinical investigation for cerebral aneurysm clipping.

Objective: The overall aim of this study was to demonstrate the potential benefit of a novel mixed-reality-head-mounted display (MR-HMD) on the spatial orientation of surgeons.

Methods: In a prospective clinical investigation, the authors applied for the first time a new multicamera navigation technology in an operating room setting that allowed them to directly compare MR-HMD navigation to standard monitor navigation. In the study, which included 14 patients with nonruptured middle cerebral artery aneurysms, the authors investigated how intuitively and effectively surgical instruments could be guided in 5 different visual navigation conditions.

Optimizing the fitting-surface preparation of zirconia restorations for bonding to dentin.

Objectives: The aim of this study was to identify the relative strengths and weaknesses of different interfaces within the multilayer structure of a zirconia crown restoration when applying different surface pretreatments. These include the influence on shear strengths of different air abrasion protocols, glaze-on techniques, zirconia primers and self-adhesive cements for either the complex structure: zirconia / self adhesive resin composite cement (RCC) / bovine dentin substrate (part 1) or the RCC / zirconia substrate (part 2).

Methods: In Part 1, zirconia discs, pretreated by either glaze-on techniques or air abrasion using Rocatec™ Soft, were bonded to bovine dentin substrates with different self-adhesive RCCs.

A comprehensive clinico-radiological, neuropsychological and biomechanical analysis approach to patients with idiopathic normal pressure hydrocephalus.

Background: A systematic approach to patients with suspected idiopathic normal pressure hydrocephalus (iNPH) is essential to recognize the subset of patients who may benefit from ventriculoperitoneal shunt surgery (VPS). Quantitative biomechanical analysis of gait and balance (QBAGB) may help objectify the response to the cerebrospinal fluid tap test (CSF-TT) and VPS outcome after 3 months and support identification of candidates for VPS.

Methods: We retrospectively reviewed data from all patients with probable iNPH who 1) underwent clinico-radiological and neuropsychological assessments using validated scales (iNPH Scale and iNPH Radscale) at our centre in the period from January to December 2018; and 2) had completed QBAGB before CSF-TT ('baseline'), shortly after CSF-TT, and at three months after either VPS or conservative treatment.

Do male athletes with already high initial haemoglobin mass benefit from 'live high-train low' altitude training?

What is the central question of this study? It has been assumed that athletes embarking on an 'live high-train low' (LHTL) camp with already high initial haemoglobin mass (Hb ) have a limited ability to increase their Hb further post-intervention. Therefore, the relationship between initial Hb and post-intervention increase was tested with duplicate Hb measures and comparable hypoxic doses in male athletes. What is the main finding and its importance? There were trivial to moderate inverse relationships between initial Hb and percentage Hb increase in endurance and team-sport athletes after the LHTL camp, indicating that even athletes with higher initial Hb can reasonably expect Hb gains post-LHTL.

Individual hemoglobin mass response to normobaric and hypobaric "live high-train low": A one-year crossover study.

The purpose of this research was to compare individual hemoglobin mass (Hb) changes following a live high-train low (LHTL) altitude training camp under either normobaric hypoxia (NH) or hypobaric hypoxia (HH) conditions in endurance athletes. In a crossover design with a one-year washout, 15 male triathletes randomly performed two 18-day LHTL training camps in either HH or NH. All athletes slept at 2,250 meters and trained at altitudes <1,200 meters.

Surgical technique for venous patch aneurysms with no neck in a rabbit model.

Background: Animal experimental studies are crucial for the development of endovascular devices and embolization techniques for intracranial aneurysms. The aim of the study was to describe the surgical creation technique for an aneurysm with a dilated shape and no definable aneurysm neck. The model should be reproducible in size and shape and stay patent over a long period of time.

The Impact of Hyperoxia on Human Performance and Recovery.

Hyperoxia results from the inhalation of mixtures of gas containing higher partial pressures of oxygen (O) than normal air at sea level. Exercise in hyperoxia affects the cardiorespiratory, neural and hormonal systems, as well as energy metabolism in humans. In contrast to short-term exposure to hypoxia (i.

Same Performance Changes after Live High-Train Low in Normobaric vs. Hypobaric Hypoxia.

Purpose: We investigated the changes in physiological and performance parameters after a Live High-Train Low (LHTL) altitude camp in normobaric (NH) or hypobaric hypoxia (HH) to reproduce the actual training practices of endurance athletes using a crossover-designed study.

Methods: Well-trained triathletes (n = 16) were split into two groups and completed two 18-day LTHL camps during which they trained at 1100-1200 m and lived at 2250 m (P i O2 = 111.9 ± 0.

Association of Hematological Variables with Team-Sport Specific Fitness Performance.

Purpose: We investigated association of hematological variables with specific fitness performance in elite team-sport players.

Methods: Hemoglobin mass (Hbmass) was measured in 25 elite field hockey players using the optimized (2 min) CO-rebreathing method. Hemoglobin concentration ([Hb]), hematocrit and mean corpuscular hemoglobin concentration (MCHC) were analyzed in venous blood.

Similar Hemoglobin Mass Response in Hypobaric and Normobaric Hypoxia in Athletes.

Purpose: To compare hemoglobin mass (Hb(mass)) changes during an 18-d live high-train low (LHTL) altitude training camp in normobaric hypoxia (NH) and hypobaric hypoxia (HH).

Methods: Twenty-eight well-trained male triathletes were split into three groups (NH: n = 10, HH: n = 11, control [CON]: n = 7) and participated in an 18-d LHTL camp. NH and HH slept at 2250 m, whereas CON slept, and all groups trained at altitudes <1200 m.

Influence of Hypoxic Interval Training and Hyperoxic Recovery on Muscle Activation and Oxygenation in Connection with Double-Poling Exercise.

Here, we evaluated the influence of breathing oxygen at different partial pressures during recovery from exercise on performance at sea-level and a simulated altitude of 1800 m, as reflected in activation of different upper body muscles, and oxygenation of the m. triceps brachii. Ten well-trained, male endurance athletes (25.

"Live High-Train Low and High" Hypoxic Training Improves Team-Sport Performance.

Purpose: This study aims to investigate physical performance and hematological changes in 32 elite male team-sport players after 14 d of "live high-train low" (LHTL) training in normobaric hypoxia (≥14 h·d at 2800-3000 m) combined with repeated-sprint training (six sessions of four sets of 5 × 5-s sprints with 25 s of passive recovery) either in normobaric hypoxia at 3000 m (LHTL + RSH, namely, LHTLH; n = 11) or in normoxia (LHTL + RSN, namely, LHTL; n = 12) compared with controlled "live low-train low" (LLTL; n = 9) training.

Methods: Before (Pre), immediately after (Post-1), and 3 wk after (Post-2) the intervention, hemoglobin mass (Hbmass) was measured in duplicate [optimized carbon monoxide (CO) rebreathing method], and vertical jump, repeated-sprint (8 × 20 m-20 s recovery), and Yo-Yo Intermittent Recovery level 2 (YYIR2) performances were tested.

Results: Both hypoxic groups similarly increased their Hbmass at Post-1 and Post-2 in reference to Pre (LHTLH: +4.

Comparison of "Live High-Train Low" in normobaric versus hypobaric hypoxia.

We investigated the changes in both performance and selected physiological parameters following a Live High-Train Low (LHTL) altitude camp in either normobaric hypoxia (NH) or hypobaric hypoxia (HH) replicating current "real" practices of endurance athletes. Well-trained triathletes were split into two groups (NH, n = 14 and HH, n = 13) and completed an 18-d LHTL camp during which they trained at 1100-1200 m and resided at an altitude of 2250 m (PiO2  = 121.7±1.

Does hyperoxic recovery during cross-country skiing team sprints enhance performance?

Purpose: This study aimed to determine the acute responses of breathing oxygen-enriched air during the recovery periods of a simulated 3 × 3-min cross-country skiing team sprint competition at simulated low altitude.

Methods: Eight well-trained male endurance athletes performed two 3 × 3-min team sprint simulations on a double-poling ergometer at simulated altitude set at ∼ 1800 m. During the recovery periods between the 3 × 3-min sprints, all the athletes inhaled either hyperoxic (FiO2 = 1.

Does upper-body compression improve 3 × 3-min double-poling sprint performance?

Purpose: To evaluate whether upper-body compression affects power output and selected metabolic, cardiorespiratory, hemodynamic, and perceptual responses during three 3-min sessions of double-poling (DP) sprint.

Method: Ten well-trained male athletes (25 ± 4 y, 180 ± 4 cm, 74.6 ± 3.

Primer on preclinical instruction and evaluation.

This review summarizes the available literature for both instruction and evaluation of the novice dental and dental hygiene preclinical student. Effective instruction for dental and dental hygiene instrumentation requires knowledge of motor skills theory and mechanisms of fine motor skills attainment. The novice learner requires small, explicit steps that clearly define production.